Rapid and high throughput detection of HBV YMDD mutants with fluorescence polarization
نویسندگان
چکیده
منابع مشابه
Rapid and high throughput detection of HBV YMDD mutants with fluorescence polarization.
AIM To develop a simple and rapid detection of HBV gene variants and prediction of lamivudine-resistance in patients. METHODS Initially, plasmids harboring the wild-type or mutant HBV DNA fragments were used in a model system. The technique was then applied to clinical samples for an analysis of YMDD mutations. The sera were extracted from chronic hepatitis patients who had received lamivudin...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2003
ISSN: 1007-9327
DOI: 10.3748/wjg.v9.i10.2344